I'd take some time to share my tips on hard city survivial with 100% product reinvention, no seaport and many competitors, only semi-product for import companies.
As i'll have not the time to do all this evening i'll add some posts in the next days if needed

First rules : take care of your money and remember that you need some inhabitants in your city so you must have good QoL to attract them.
The 3 first months there will be no inhabitants, time for public buildings to pump QoL, so don't invest so much in farms&factories
Remember too that there will be very few researchers for R&D. No computer means no digital products for now.
my steps (STOP the TIME) :
1) i identify a 6*6 square in the middle of the map and buy it for my company.
2) on north side i put 2 publics like city hall and police station to bring some costumer traffic
3) on south side i put a big public like hospital for same reasons
4) on east side mayor build 2 appartements and a tennis court
5) on west side mayor build 1 commercial building
6) build the other publics (but not university nor museum for now), about sports tennis court is enough to start
7) setup mayor parameters : 40% rent for appartements and commercials, allow maxium immigrants to speed your city grow.
8) micromanage publics to give them adequate budget, we need to make economies but to pump up QoL. So you'll have to change it 2-3 times a month
9) build a farm (small is safer, big is better for long run, depands of your money supply). (i play often with real world so i start with fishs)
10) build a store to sell your farm product at low price for now. Remember food is very important at the begining. no food = no life
11) as we have import companies here it can make things easier to start a small factory, some food products are unlock by design. but i don't use this trick for now. as money can be a pain. no bank NPC = no money to borrow (but maybe you'll be more lucky than me).
12) restrict buildings aera to only commercials and residentials near your setup (you don't want pollution in town center), specifi factory zone and farm zones on suburbs

=> unpause the game and play il slow speed
1) AI should begin to build some farms or R&D and buy some land (but AI is very shy till you have an average city)
2) no new inhabitants, no sale, no stress

3) after 3 months you'll begin to have some costumers
4) micromanage your store, you can add training in your store and a little in your farm
5) as soon as budget is nearly neutral i build a second farm near the first one to product other foods (no vegetables or fruits as too long to be available, and AI often try them)
6) check city publics budget (you can automate them to keep 80% QoL)
7) once appartements and commercial buildings are full build 1 more (slow scaling)
8) if no AI build a media firm, build one with your mayor as it can be a big money supply for your town
9) if you play a modded game and AI don't spam the farms you can try a 3rd one and improve training to get better/more expensive products.
10) try to R&D easy leather products that need only leather (as you can afford a farm for leather but not a mine). If you can have cheap wood, bed is always a cheap option too.
11) remember to check AI R&D and productions to avoid competition now, you can't afford to lower your prices for now.
12) if you have extra cash build your HQ and organize a global training to improve all your farms quality product in one shot. It can be really rentable (remember to increase your sellign prices then)
(if you have critical cash issue you can sell a part of your start land, but try to avaid it to be able to build cheap commercials later)
next step next time
